Effects of some plants extracts in growth of some dermatophytes

Abstract

The results showed that the different plant extracts (aqueous, alcoholic, and acetone) had a high (good) inhibitory effectiveness, as the alcoholic extract of the seeds of the T.chebula plant showed that the diameters of the fungal colonies A.flavus, A.niger, T.mentagrophytes, T.rubrum, M.canis (70, 68, 40, 33, and 25) mm, respectively, at a concentration of 1 mg/ml, while the average diameters of fungal colonies were (48, 40, 0, 0, and 0) mm, respectively, at a concentration of 7 mg/ml, while the average diameters of fungal colonies were zero with a percentage of inhibition. Its amount is 100% at a concentration of 20 mg/ml. As for the acetone extract, it also showed a high inhibitory activity against fungal species, as the diameters of the fungal colonies were (75, 70, 45, 38 and 31) mm, respectively, at a concentration of 1 mg/ml, while they were (52, 43, 10, 0, 0) mm, respectively, at a concentration of 7 mg/ml, while it was zero with a 100% inhibition rate at a concentration of 20 mg/ml. The aqueous extract also showed high inhibition effectiveness against fungal species, as the fungal colony diameters were (80, 72, 45, 42, and 35) mm, respectively, at a concentration of 1 mg/ml, while it reached (57, 45, 21, 14, and 0) mm, respectively, at a concentration of 7 mg/ml, while it reached zero with a 100% inhibition rate at a concentration of 20 mg/ml. In addition, the minimum inhibitory concentration (MIC) of the alcoholic extract of the T.chebula plant was determined. as it was found through conducting a toxicological test for plant extracts that the plants did not contain cytotoxic effects.