A Synthetic Approach to Parkinson’s Disease Drugs: Pramipexole and Rotigotine

Authors

  • Rasha Jwad Department of Chemistry, College of Science, Al-Nahrain University https://orcid.org/0000-0001-8838-4181
  • Nadia Salih Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan, Malaysia, 43600 Bangi, Selangor, Malaysia
  • Jumat Salimon Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan, Malaysia, 43600 Bangi, Selangor, Malaysia

Keywords:

Pramipexole, rotigotine, asymmetric synthesis, Parkinson’s disease

Abstract

In recent years, there has been numerous notable changes in Parkinson's disease medication. Researchers have produced new medications and gained a firm understanding of how to employ existing treatments. This has made a major impact on the lives of those suffering from the condition. Parkinson's medicine is used to treat the symptoms by compensating for the brain's loss of dopamine. Medication, particularly in the early stages of Parkinson's disease, can significantly lessen symptoms. This review displays one of the main categories of the antiparkinson agents, as it focuses on the synthetic methodology of two important dopaminergic medications namely; pramipexole and rotigotine.

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Published

2023-07-24 — Updated on 2023-07-24

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